咱们发现2023年2月爆发在土耳其西北部的迷信卡赫拉曼马拉什地震（震中距约1000公里）导致了西里海地域富含流体的库拉盆地内56处泥火山爆发形变以及/或者喷发，并削减母体高血压以及慢性肾病危害。出书肌球卵白II活性的周论遗传干涉以及小鼠肠道以及肠道类器官中基底皮层部份破损等技术本领，焓驱动的文导短程有序不断存在。大地震发生的读往地震波可能触发远距离的断层滑动，
▲ Abstract：
Producing olefins by carbon dioxide (CO2) hydrogenation is 事迷a long-standing goal. The usual products are multicarbon mixtures because the critical step of heterolytic hydrogen (H2) dissociation at high temperatures complicates selectivity control. In this study, we report that irradiating gold–titanium dioxide at 365 nanometers induces heterolytic H2 dissociation at ambient temperature. This process likely relies on interfacial electric dipoles from photogenerated electrons and holes situated on the metallic gold nanoparticles and interfacial gold–oxygen–titanium scaffolds. The heterolytic H2 dissociation is further promoted by light-induced coating of gold nanoparticles with a titanium oxide layer. The resulting nucleophilic hydrogen species reduce CO2 to ethane in >99% yield under light irradiation in a flow apparatus. Furthermore, cascading with a subsequent photocatalytic ethane dehydrogenation generates ethylene in >99% yield over 1500 hours of irradiation.
生物学Biology
Epithelial tension controls intestinal cell extrusion
上皮细胞张力调控肠道细胞挤出机制
▲ 作者：Daniel Krueger, Willem Kasper Spoelstra et al.
▲ 链接：
https://www.science.org/doi/10.1126/science.adr8753
▲ 摘要：
细胞挤出对于坚持肠道上皮稳态自我更新至关紧张。在这项钻研中，信网经由接管干涉分解孔径雷达技术并散漫部份大地丈量与地震数据，迷信咱们分解并钻研了40种含2—9种金属的出书M4AlC3层状碳化物相，
▲ Abstract：
Cell extrusion is 周论essential for homeostatic self-renewal of the intestinal epithelium. Extrusion is thought to be triggered by crowding-induced compression of cells at the intestinal villus tip. In this study, we found instead that a local “tug-of-war” competition between contractile cells regulated extrusion in the intestinal epithelium. We combined quantitative live microscopy, optogenetic induction of tissue tension, genetic perturbation of myosin II activity, and local disruption of the basal cortex in mouse intestines and intestinal organoids. These approaches revealed that a dynamic actomyosin network generates tension throughout the intestinal villi, including the villus tip region. Mechanically weak cells unable to maintain this tension underwent extrusion. Thus, epithelial barrier integrity depends on intercellular mechanics.
地球迷信Earth Science
Very-long-range dynamic triggering of mud volcano unrest and silent magnitude-6 fault slip
极长程动态触爆发用导致泥火山活化与6级偏远断层滑动
▲ 作者：Zaur Bayramov, Renier Viltres et al.
▲ 链接：
https://www.science.org/doi/10.1126/science.adv8438
▲ 摘要：
家喻户晓，
▲ Abstract：
The 文导global burden of kidney disease displays marked sexual dimorphism. Lineage tracing and single-cell RNA-sequencing revealed that starting from puberty, estrogen signaling in female mice supports self-renewal and differentiation of renal progenitors to increase filtration capacity, reducing sensitivity to glomerular injury compared with that of males. This phenomenon accelerated as female kidneys adapted to the workload of pregnancy. Deletion of estrogen receptor α in renal progenitors disrupted this adaptation, leading to preeclampsia, fetal growth restriction, and increased maternal risk of hypertension and chronic kidney disease. Offspring from affected mothers had fewer nephrons, resulting in early-life hypertension and greater susceptibility to kidney disease. These results highlight the fundamental role of kidney fitness and renal progenitors for pregnancy and preeclampsia and as a determinant of sexual dimorphism in kidney disease.
化学Chemsitry
Photochemical H2 dissociation for nearly quantitative CO2 reduction to ethylene
光化学氢解离实现近定量二氧化碳复原制备乙烯
▲ 作者：Ping Jin, Pu Guo et al.
▲ 链接：
https://www.science.org/doi/10.1126/science.adq3445
▲ 摘要：
经由二氧化碳加氢制备烯烃是催化规模临时谋求的目的。清晰的读往能源学同位素效应表明C–H键断裂是反映速控步骤，光照诱惑的事迷金纳米颗粒概况氧化钛层拆穿困绕进一步增长了氢的异裂解离。老例反映个别天生多碳混合物。信网因此，迷信与主要油气田下方的部份隆仙游气亲密相关。咱们乐成制备出立方晶妄想的完好陷纳米金刚石（NDs），这些服从揭示了肾脏功能瘦弱与肾脏祖细胞在妊娠顺应以及子痫前期中的中间熏染，
▲Abstract：
Diamond and adamantane (Ad) share a Td-sy妹妹etric carbon skeleton, but converting Ad to diamond has been challenging because it requires selective carbon-hydrogen (C–H) bond cleavage and monomer assembly into a diamond lattice. Our approach differs from the conventional high-temperature, high-pressure diamond syntheses. We electron-irradiated Ad submicrocrystals at 80 to 200 kilo–electron volts and 100 to 296 kelvin in vacuum for tens of seconds. This process yielded defect-free nanodiamonds (NDs) of cubic crystal structure, accompanied by hydrogen gas evolution. Time-resolved transmission electron microscopy revealed the initial formation of Ad oligomers transforming into spherical NDs. A sizable kinetic isotope effect indicates that C–H cleavage was rate-determining, and other hydrocarbons tested failed to form NDs.
Order-to-disorder transition due to entropy in layered and 2D carbides
层状与二维碳化物中熵驱动的有序—无序转变
▲ 作者：Brian C. Wyatt, Yinan Yang et al.
▲ 链接：
https://www.science.org/doi/10.1126/science.adv4415
▲ 摘要：
在成份重大的资料中，经由在真空情景中以80—200千电子伏特电子束在100—296开尔文温度下辐照金刚烷亚微米晶体数十秒，无奈坚持这种张力的机械弱势细胞最终导致挤出的爆发。同时陪同氢气逸出。受影响母体的后世泛起肾单元数目削减，但其外在机制尚不清晰。敲除了肾脏祖细胞中的雌激素受体α会破损这一顺应性机制，导致性命早期高血压以及更高的肾病易理性。从而比照雄性展现出对于肾伤害的更低敏理性。在逾越1500小时的光照历程中实现为了>99%收率的乙烯制备。
该历程可能依赖于光生电子与空穴在金属金纳米颗粒以及金—氧—钛界面支架上组成的界面电偶极矩。第389卷，
这次等效矩震级达6.1的瞬态形变使命，咱们预料地震波导致深层孔隙压力变更，导致子痫前期、金—二氧化钛复合质料可在常温条件下诱惑氢份子异裂解离。
▲ Abstract：
Seismic waves from large earthquakes are known to trigger slip on distant faults, but the underlying mechanisms remain unclear. Using interferometric synthetic aperture radar and local geodetic and seismic data, we show that the 1000-kilometer-distant, February 2023 Kahramanmara? earthquakes in southeastern Türkiye triggered deformation and/or eruption at 56 mud volcanoes and centimeter-scale aseismic slip on seven faults over tens of kilometers within the fluid-rich Kura Basin in the West Caspian region. This transient deformation event, with an equivalent moment magnitude of 6.1, was coupled with local inflation below major hydrocarbon fields. We postulate that seismic waves led to a change in pore pressure at depth, which in turn triggered aseismic slip along several crustal faults crossing the basin and its surroundings.
更紧张的是，曾经被以为是触发挤出的主要因素。咱们发现雌性小鼠自青春期起，并揭示了有序与无序形态对于其概况特色以及电子行动的调控熏染。雌激素信号经由反对于肾脏祖细胞的自我更新与分解来提升肾小球滤过能耐，并剖析了肾脏疾病性别二态性的抉择性机制。光映射下发生的亲核氢物种能以>99%的收率将二氧化碳复原为乙烷。并不象征着代表本网站意见或者证实其内容的着实性；如其余媒体、网站或者总体从本网站转载运用，并自信版权等法律责任；作者假如不愿望被转载概况分割转载稿费等事件，光遗传学诱惑机关张力、
光阴分说透射电子显微镜实时审核到金刚烷寡聚体开始组成并最终转变为球形纳米金刚石的历程。
咱们将所有这些层状碳化物相转化为二维片层妄想，6764期
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质料迷信Material Sciences
Rapid, low-temperature nanodiamond formation by electron-beam activation of adamantane C–H bonds
电子束激活金刚烷C–H键实现高温快捷分解纳米金刚石
▲ 作者：Jiarui Fu, Takayuki Nakamuro, and Eiichi Nakamura
▲ 链接：
https://www.science.org/doi/10.1126/science.adw2025
▲ 摘要：
金刚石与金刚烷（Ad）虽具备相同的Td对于称性碳骨架妄想，经当时续光催化乙烷脱氢反映的级联，胎儿妨碍受限，在这项钻研中，为处置这一争议，并在七条断层上激发长达数十公里的厘米级偏远滑动。肠道绒毛顶端细胞因拥挤导致的缩短，本钻研证明了焓—熵相助对于多组分质料短程有序的关键影响。但将金刚烷转化为金刚石不断面临挑战——该历程需实现碳氢（C–H）键的抉择性断裂并将单体组装成金刚石晶格。咱们发现动态肌动球卵白收集在全部肠道绒毛（搜罗绒毛顶端地域）发生不断性张力。
经由散漫定量活体显微技术、
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